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PHARMACEUTICAL > Topics

Subject: **Anesthetic
Replies: 8 Views: 789

oxide_vx 16.01.12 - 09:02pm
This process occurs through an oxidation, which regenerates the pyrrolinium cation and formation of an enolate anion, and an intramolecular Mannich reaction. The tropane ring system undergoes hydrolysis, SAM-dependent methylation, and reduction via NADPH for the formation of methylecgonine. The benzoyl moiety required for the formation of the cocaine diester is synthesized from phenylalanine via cinnamic acid. *

oxide_vx 16.01.12 - 09:03pm
Benzoyl-CoA then combines the two units to form cocaine. *

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